Antimicrobial agent

Flagil is sometimes prescribed as one of the antibiotics in the complex therapy of Helicobacter pylori eradication. Flagyl is not used in the eradication of Helicobacter pylori outside the special schemes, without drugs that reduce stomach acidity. Flagyl is also not used in any form to treat stomach ulcer and duodenal ulcer and gastritis in the absence of a patient Helicobacter pylori. Flagyl (metronidazole) is an antibiotic. It fights bacteria in your body. Flagyl is used to treat bacterial infections of the vagina, stomach, skin, joints and respiratory tract. This drug will not treat vaginal yeast infections.

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Special instructions

Because taking the drug with alcohol at the same time may have an effect similar to that of disulfiram (fever, vomiting, tachycardia), patients should be warned not to drink alcoholic beverages or medication containing alcohol during Flagilom's treatment. Prolonged administration of the drug should preferably be done under the control of a blood formula. In leukopenia, the possibility of continuing treatment depends on the risk of infection. Treatment of trichomonadal vaginitis in women and trichomonadal urethritis in men should be avoided. Simultaneous treatment of sexual partners is essential. Treatment does not stop during menstruation. After the treatment of trichomoniasis, control tests should be performed for 3 consecutive cycles before and after menstruation. After treatment of giardiasis, if symptoms persist, perform 3 fecal tests at intervals of several days after 3-4 weeks (some successfully treated patients may still have lactose intolerance caused by invasion for several weeks or months, recalling the symptoms of giardiasis). Treatment should be discontinued if ataxia, dizziness, hallucinations, or neurological status worsens. It should be taken into account that metronidazole can immobilize treponemes, which leads to Nelson's false positive test. Influence on driving ability and driving mechanisms Due to the possibility of dizziness and other side effects associated with taking the drug, it is recommended to refrain from driving the car and other mechanisms.

Medicinal interaction

Ethanol intolerance causes the same effect as disulfiram. Simultaneous use with disulfiram can lead to the development of various neurological symptoms (the interval between prescriptions is at least 2 weeks). It enhances the action of indirect anticoagulants, which leads to increased prothrombin production time. Cimetidine suppresses the metabolism of metronidazole, which may lead to increased serum concentrations and increased risk of side effects. Simultaneous administration of medications stimulating microsomal oxidation enzymes in the liver (phenobarbital, phenytoin) may